hrp0092p2-235 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

A Case of Gonadotropin-Independent Precocious Puberty Due to Germ Cell Tumor in the Frontal Lobe

Hacihamdioglu Bulent , Yalcin Koray , Suna Celen Safiye , Hazar Volkan

Introduction: It is known that gonadotropin-independent or peripheral precocious puberty (PPP) may develop due to tumors that secrete beta human chorionic gonadotropin (Beta-HCG). These tumors can be located in gonads, liver, mediastinum or central nervous system. HCG-producing tumors of the central nervous system are rare, most commonly seen in the suprasellar and pineal regions. However, any germ cell tumor (GCT) containing the syncytiotroblastic giant cell ...